InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndufs6

Summary

InnateDB Protein

IDBP-165542.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufs6

Protein Name

NADH dehydrogenase (ubiquinone) Fe-S protein 6

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022097

InnateDB Gene

IDBG-165540 (Ndufs6)

Protein Structure

UniProt Annotation

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006631	fatty acid metabolic process
GO:0006936	muscle contraction
GO:0010259	multicellular organismal aging
GO:0022904	respiratory electron transport chain
GO:0035264	multicellular organism growth
GO:0061458	reproductive system development
GO:0070584	mitochondrion morphogenesis
GO:0072358	cardiovascular system development