Version 5.4
| Mus musculus Gene: Ltb4r1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-165796.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ltb4r1 | ||||||||
| Gene Name | leukotriene B4 receptor 1 | ||||||||
| Synonyms | BLT1; BLTR; Ltb4r; mBLTR | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000046908 | ||||||||
| Encoded Proteins |
leukotriene B4 receptor 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| InnateDB Annotation from Orthologs | |||||||||
| Summary |
[Homo sapiens] LTB4R (BLT1) is a high-affinity leukotriene B4 (LTB4) receptor that is expressed in a variety of immune cells such as neutrophils, macrophages and dendritic cells. LTB4-LTB4R signaling plays a pivotal role in macrophage phagocytosis and innate immunity.
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| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213903:
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 14:55765962-55768494 | ||||||||
| Strand | Forward strand | ||||||||
| Band | C3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
GPCR downstream signaling pathway
Signaling by GPCR pathway
Leukotriene receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
Eicosanoid ligand-binding receptors pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Leukotriene receptors pathway
Eicosanoid ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Signaling by GPCR pathway
Eicosanoid ligand-binding receptors pathway
Leukotriene receptors pathway
Signal Transduction pathway
G alpha (q) signalling events pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Class A/1 (Rhodopsin-like receptors) pathway
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| KEGG |
Neuroactive ligand-receptor interaction pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | O88855 | ||||||||
| TrEMBL | A7VJD3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 16995 | ||||||||
| UniGene | Mm.20853 | ||||||||
| RefSeq | NM_008519 XM_006518666 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS27129 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1309472 | ||||||||
| MGI Symbol | Ltb4r1 | ||||||||
| EMBL | AB008049 AF044030 AF077673 AF110104 BC064063 CH466535 | ||||||||
| GenPept | AAC61677 AAD09817 AAD43002 AAH64063 BAF80084 EDL36238 | ||||||||
| RNA Seq Atlas | 16995 | ||||||||