Version 5.4
Mus musculus Gene: Slc16a2
Summary
InnateDB Gene IDBG-165879.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc16a2
Gene Name solute carrier family 16 (monocarboxylic acid transporters), member 2
Synonyms AW105741; Mct8; Xpct
Species Mus musculus
Ensembl Gene ENSMUSG00000033965
Encoded Proteins
IDBP-165881
solute carrier family 16 (monocarboxylic acid transporters), member 2
IDBP-533606
solute carrier family 16 (monocarboxylic acid transporters), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147100:
This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:103697414-103821965
Strand Reverse strand
Band D
Transcripts
ENSMUST00000042664 ENSMUSP00000037629
ENSMUST00000148684 ENSMUSP00000116889
ENSMUST00000171837
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015293 symporter activity
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000147100
View Gene Order
ENSBTAG00000002585
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.388973 Mm.475003
RefSeq NM_009197
OMIM
CCDS CCDS30330
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca