Version 5.4
Bos taurus Gene: SLC16A2
Summary
InnateDB Gene IDBG-635527.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC16A2
Gene Name monocarboxylate transporter 8
Synonyms MCT8
Species Bos taurus
Ensembl Gene ENSBTAG00000002585
Encoded Proteins
IDBP-687374
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147100:
This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:81604863-81621189
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003345 ENSBTAP00000003345
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000147100
View Gene Order
ENSMUSG00000033965
View Gene Order
Cross-References
SwissProt
TrEMBL B2DG20 F1MM56
UniProt Splice Variant
Entrez Gene 535872
UniGene Bt.108509 Bt.62976
RefSeq NM_001206939
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB435505 DAAA02072549
GenPept BAG31382
RNA Seq Atlas 535872

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca