Version 5.4
Mus musculus Gene: Cyp4f39
Summary
InnateDB Gene IDBG-165971.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cyp4f39
Gene Name cytochrome P450, family 4, subfamily f, polypeptide 39
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000061126
Encoded Proteins
IDBP-165973
cytochrome P450, family 4, subfamily f, polypeptide 39
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171954:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:32468462-32492479
Strand Forward strand
Band B1
Transcripts
ENSMUST00000003413 ENSMUSP00000003413
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
Biological Process
GO:0008150 biological_process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171954
View Gene Order
ENSBTAG00000047933
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150420
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
REACT_147851
Arachidonic acid metabolism pathway
REACT_13814
Fatty acids pathway
REACT_13425
Miscellaneous substrates pathway
REACT_13645
Eicosanoids pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_13567
Cytochrome P450 - arranged by substrate type pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
REACT_13705
Phase 1 - Functionalization of compounds pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q8BGU0
UniProt Splice Variant
Entrez Gene 320997
UniGene Mm.130900
RefSeq NM_177307 XM_006524423
OMIM
CCDS CCDS28618
HPRD
IMGT
MGI ID MGI:2445210
MGI Symbol Cyp4f39
EMBL AK028950 AK037192 CH466640 CT485616
GenPept BAC26210 BAC29745 EDL40309
RNA Seq Atlas 320997

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca