Mus musculus Gene: Uprt
Summary
InnateDB Gene IDBG-166171.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Uprt
Gene Name uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000073016
Encoded Proteins
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000094841:
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:104482818-104507490
Strand Forward strand
Band D
Transcripts
ENSMUST00000087867 ENSMUSP00000085175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006222 UMP biosynthetic process
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0009116 nucleoside metabolic process
GO:0032868 response to insulin
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Pyrimidine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Pyrimidine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt B1AVZ0
TrEMBL
UniProt Splice Variant
Entrez Gene 331487
UniGene Mm.438275 Mm.459517
RefSeq NM_001081189
OMIM
CCDS CCDS41093
HPRD
IMGT
MGI ID MGI:2685620
MGI Symbol Uprt
EMBL AL731717 BC147845 BC147853
GenPept AAI47846 AAI47854 CAM27338
RNA Seq Atlas 331487