Version 5.4
Homo sapiens Gene: SLC2A3
Summary
InnateDB Gene IDBG-16633.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC2A3
Gene Name solute carrier family 2 (facilitated glucose transporter), member 3
Synonyms GLUT3
Species Homo sapiens
Ensembl Gene ENSG00000059804
Encoded Proteins
IDBP-16635
solute carrier family 2 (facilitated glucose transporter), member 3
IDBP-600949
solute carrier family 2 (facilitated glucose transporter), member 3
IDBP-593004
solute carrier family 2 (facilitated glucose transporter), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:7919230-7936275
Strand Reverse strand
Band p13.31
Transcripts
ENST00000075120 ENSP00000075120
ENST00000479059
ENST00000486749
ENST00000469295
ENST00000490763
ENST00000495813
ENST00000476634
ENST00000543435
ENST00000544291 ENSP00000440750
ENST00000544936 ENSP00000441496
ENST00000541671
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005355 glucose transmembrane transporter activity
GO:0022857 transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006766 vitamin metabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0006810 transport
GO:0008645 hexose transport
GO:0015758 glucose transport
GO:0019852 L-ascorbic acid metabolic process
GO:0044281 small molecule metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003153
View Gene Order
ENSBTAG00000004556
Not yet available
Pathways
NETPATH
REACTOME
REACT_19343
Facilitative Na+-independent glucose transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_212
Glucose transport pathway
REACT_9441
Hexose transport pathway
REACT_11202
Vitamin C (ascorbate) metabolism pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_169312
Defective HLCS causes multiple carboxylase deficiency pathway
REACT_169313
Defective MUT causes methylmalonic aciduria mut type pathway
REACT_169316
Defective MMAA causes methylmalonic aciduria type cblA pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_169120
Defective TCN2 causes hereditary megaloblastic anemia pathway
REACT_11238
Metabolism of water-soluble vitamins and cofactors pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_169280
Defective AMN causes hereditary megaloblastic anemia 1 pathway
REACT_169149
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG pathway
REACT_169363
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF pathway
REACT_169178
Defective CD320 causes methylmalonic aciduria pathway
REACT_169429
Defects in cobalamin (B12) metabolism pathway
REACT_169169
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC pathway
REACT_169238
Defects in biotin (Btn) metabolism pathway
REACT_169403
Defective BTD causes biotidinase deficiency pathway
REACT_169415
Defective GIF causes intrinsic factor deficiency pathway
REACT_169385
Defects in vitamin and cofactor metabolism pathway
REACT_169132
Defective CUBN causes hereditary megaloblastic anemia 1 pathway
REACT_169256
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD pathway
REACT_169439
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE pathway
REACT_111217
Metabolism pathway
REACT_169318
Defective MMAB causes methylmalonic aciduria type cblB pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_116125
Disease pathway
REACT_200833
Glycogen storage diseases pathway
REACT_11193
Metabolism of vitamins and cofactors pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.419240 Hs.573294 Hs.595564 Hs.680728
RefSeq NM_006931
HUGO
OMIM
CCDS CCDS8586
HPRD 00686
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca