Version 5.4
Mus musculus Gene: Senp7
Summary
InnateDB Gene IDBG-166404.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Senp7
Gene Name SUMO1/sentrin specific peptidase 7
Synonyms 2410152H17Rik; 2810413I22Rik; 2900036C23Rik; 6030449K19Rik; AI790676; mKIAA1707
Species Mus musculus
Ensembl Gene ENSMUSG00000052917
Encoded Proteins
IDBP-166406
SUMO1/sentrin specific peptidase 7
IDBP-166408
SUMO1/sentrin specific peptidase 7
IDBP-166410
SUMO1/sentrin specific peptidase 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138468:
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:56075409-56190011
Strand Forward strand
Band C1.1
Transcripts
ENSMUST00000089362 ENSMUSP00000086779
ENSMUST00000089360 ENSMUSP00000086776
ENSMUST00000049128 ENSMUSP00000043023
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0008150 biological_process
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138468
View Gene Order
ENSBTAG00000016932
Not yet available
Cross-References
SwissProt Q8BUH8
TrEMBL
UniProt Splice Variant
Entrez Gene 66315
UniGene Mm.255784 Mm.398052
RefSeq NM_025483 XM_006522456 NM_001003971 NM_001003972 NM_001003973
OMIM
CCDS CCDS28222 CCDS28221 CCDS28223
HPRD
IMGT
MGI ID MGI:1913565
MGI Symbol Senp7
EMBL AK085060 AK122542 BC058593
GenPept AAH58593 BAC39352 BAC65824
RNA Seq Atlas 66315

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca