Version 5.4
Mus musculus Gene: Cxcr1
Summary
InnateDB Gene IDBG-166431.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cxcr1
Gene Name chemokine (C-X-C motif) receptor 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000048480
Encoded Proteins
IDBP-166433
chemokine (C-X-C motif) receptor 1
IDBP-790582
chemokine (C-X-C motif) receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:74191785-74194631
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000053389 ENSMUSP00000049714
ENSMUST00000190313 ENSMUSP00000139555
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004918 interleukin-8 receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0019959 interleukin-8 binding
Biological Process
GO:0006935 chemotaxis
GO:0007186 G-protein coupled receptor signaling pathway
GO:0031623 receptor internalization
GO:0038112 interleukin-8-mediated signaling pathway
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_250376
G alpha (i) signalling events pathway
REACT_230248
Chemokine receptors bind chemokines pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
mmu04062
Chemokine signaling pathway pathway
mmu04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.337035
RefSeq NM_178241 XM_006495956
OMIM
CCDS CCDS15041
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca