Version 5.4
Mus musculus Gene: Dmxl2
Summary
InnateDB Gene IDBG-166526.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dmxl2
Gene Name Dmx-like 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041268
Encoded Proteins
IDBP-401071
Dmx-like 2
IDBP-401070
Dmx-like 2
IDBP-534375
Dmx-like 2
IDBP-534703
Dmx-like 2
IDBP-537524
Dmx-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104093:
This gene encodes a protein with 12 WD domains. Proteins with WD domains are involved in many functions including participation in signal transduction pathways. Participation of the encoded protein in regulation of the Notch signaling pathway has been demonstrated in vitro using several human cell lines (PMID:20810660). A gene encoding a similar protein is located on chromosome 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:54365158-54501760
Strand Reverse strand
Band A5.3
Transcripts
ENSMUST00000118163 ENSMUSP00000113705
ENSMUST00000118600 ENSMUSP00000113693
ENSMUST00000154092
ENSMUST00000123709 ENSMUSP00000119959
ENSMUST00000127880 ENSMUSP00000122293
ENSMUST00000144736
ENSMUST00000128865
ENSMUST00000149709
ENSMUST00000131452 ENSMUSP00000117245
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005615 extracellular space
GO:0008021 synaptic vesicle
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000104093
View Gene Order
ENSBTAG00000000737
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.401667 Mm.93636
RefSeq NM_172771 XM_006511083 XM_006511084 XM_006511085
OMIM
CCDS CCDS52799
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca