Version 5.4
Mus musculus Gene: Ddx24
Summary
InnateDB Gene IDBG-166722.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx24
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
Synonyms 1700055J08Rik; 2510027P10Rik; AI649272
Species Mus musculus
Ensembl Gene ENSMUSG00000041645
Encoded Proteins
IDBP-166724
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
IDBP-261192
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089737:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:103407976-103425867
Strand Reverse strand
Band E
Transcripts
ENSMUST00000044923 ENSMUSP00000040890
ENSMUST00000110001 ENSMUSP00000105628
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 49 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000089737
View Gene Order
ENSBTAG00000003423
Not yet available
Cross-References
SwissProt Q9ESV0
TrEMBL F8WJA0 Q3UYV7
UniProt Splice Variant
Entrez Gene 27225
UniGene
RefSeq NM_001159502 NM_020494 XM_006515932 XM_006515933
OMIM
CCDS CCDS26129 CCDS49152
HPRD
IMGT
MGI ID MGI:1351337
MGI Symbol Ddx24
EMBL AC154347 AF214732 AK134339 BC055048 BC055317 CH466549 U46690
GenPept AAB01091 AAG02170 AAH55048 AAH55317 BAE22104 EDL18835
RNA Seq Atlas 27225

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca