Version 5.4
Homo sapiens Gene: DDX24
Summary
InnateDB Gene IDBG-17852.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDX24
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000089737
Encoded Proteins
IDBP-17856
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
IDBP-584794
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
IDBP-595634
DEAD (Asp-Glu-Ala-Asp) box polypeptide 24
IDBP-812917
DEAD (Asp-Glu-Ala-Asp) box helicase 24
IDBP-812921
DEAD (Asp-Glu-Ala-Asp) box helicase 24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:94048291-94081245
Strand Reverse strand
Band q32.12
Transcripts
ENST00000330836 ENSP00000328690
ENST00000555762
ENST00000553400
ENST00000553451
ENST00000544005 ENSP00000440623
ENST00000555054 ENSP00000452145
ENST00000556635
ENST00000555324
ENST00000621632 ENSP00000481495
ENST00000622786 ENSP00000481317
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0016070 RNA metabolic process
Cellular Component
GO:0005730 nucleolus
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041645
View Gene Order
ENSBTAG00000003423
Not yet available
Cross-References
SwissProt Q9GZR7
TrEMBL F5GYL3
UniProt Splice Variant
Entrez Gene 57062
UniGene Hs.510328 Hs.622038
RefSeq NM_020414
HUGO HGNC:13266
OMIM 606181
CCDS CCDS9918
HPRD 05860
IMGT
EMBL AF214731 AK025162 AL079302 AL136886 BC008847 BC009406 BC096826
GenPept AAG02169 AAH08847 AAH09406 AAH96826 BAB15079 CAB66820
RNA Seq Atlas 57062

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca