Version 5.4
Mus musculus Gene: Slc9a3
Summary
InnateDB Gene IDBG-167051.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc9a3
Gene Name solute carrier family 9 (sodium/hydrogen exchanger), member 3
Synonyms 9030624O13Rik; AI930210; NHE-3; NHE3
Species Mus musculus
Ensembl Gene ENSMUSG00000036123
Encoded Proteins
IDBP-167053
solute carrier family 9 (sodium/hydrogen exchanger), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000066230:
Gene Information
Type Protein coding
Genomic Location Chromosome 13:74121515-74166064
Strand Forward strand
Band C1
Transcripts
ENSMUST00000036208 ENSMUSP00000038142
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015299 solute:proton antiporter activity
GO:0015385 sodium:proton antiporter activity
GO:0030165 PDZ domain binding
Biological Process
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0006885 regulation of pH
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0031526 brush border membrane
GO:0031988 membrane-bounded vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000066230
View Gene Order
ENSBTAG00000004629
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04974
Protein digestion and absorption pathway
mmu04976
Bile secretion pathway
mmu04964
Proximal tubule bicarbonate reclamation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19314
Sodium/Proton exchangers pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa04964
Proximal tubule bicarbonate reclamation pathway
hsa04976
Bile secretion pathway
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
endothelinpathway
Endothelins
rhoa_pathway
RhoA signaling pathway
Cross-References
SwissProt
TrEMBL G3X939 Q8BZU0 Q9WUJ5
UniProt Splice Variant
Entrez Gene 105243
UniGene
RefSeq NM_001081060 XM_006517021 XM_006517022
OMIM
CCDS CCDS36731
HPRD
IMGT
MGI ID MGI:105064
MGI Symbol Slc9a3
EMBL AC154839 AF139194 AK033564 CH466563
GenPept AAD30296 BAC28362 EDL37085
RNA Seq Atlas 105243

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca