InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc9a3

Summary

InnateDB Protein

IDBP-167053.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Slc9a3

Protein Name

solute carrier family 9 (sodium/hydrogen exchanger), member 3

Synonyms

9030624O13Rik; AI930210; NHE-3; NHE3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038142

InnateDB Gene

IDBG-167051 (Slc9a3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015299	solute:proton antiporter activity
GO:0015385	sodium:proton antiporter activity
GO:0030165	PDZ domain binding

Biological Process

GO:0006812	cation transport
GO:0006814	sodium ion transport
GO:0006885	regulation of pH
GO:0035725	sodium ion transmembrane transport
GO:0055085	transmembrane transport
GO:1902600	hydrogen ion transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0031526	brush border membrane
GO:0031988	membrane-bounded vesicle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:105064

InterPro

IPR004709 Na+/H+ exchanger
IPR006153 Cation/H+ exchanger
IPR011256 Regulatory factor, effector binding domain
IPR018410 Na+/H+ exchanger, isoforms 3/5

PFAM

PF00999

PRINTS

PR01084
PR01087

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite