Version 5.4
| Mus musculus Gene: Adamts10 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-167113.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Adamts10 | ||||||||||
| Gene Name | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10 | ||||||||||
| Synonyms | |||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000024299 | ||||||||||
| Encoded Proteins |
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142303:
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 17:33524204-33553782 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | B1 | ||||||||||
| Transcripts | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | G3UZ08 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 224697 | ||||||||||
| UniGene | Mm.29304 | ||||||||||
| RefSeq | NM_172619 XM_006524100 XM_006524101 XM_006524102 XM_006524103 XM_006524104 XM_006524105 XM_006524106 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS37566 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | MGI:2449112 | ||||||||||
| MGI Symbol | Adamts10 | ||||||||||
| EMBL | CH466660 CT030734 | ||||||||||
| GenPept | EDL10193 EDL10195 | ||||||||||
| RNA Seq Atlas | 224697 | ||||||||||