Version 5.4
Mus musculus Gene: Ahrr
Summary
InnateDB Gene IDBG-167225.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ahrr
Gene Name aryl-hydrocarbon receptor repressor
Synonyms mKIAA1234
Species Mus musculus
Ensembl Gene ENSMUSG00000021575
Encoded Proteins
IDBP-167227
aryl-hydrocarbon receptor repressor
IDBP-261959
aryl-hydrocarbon receptor repressor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000063438:
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:74211118-74292331
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000022059 ENSMUSP00000022059
ENSMUST00000109640 ENSMUSP00000105268
ENSMUST00000148438
ENSMUST00000137538
ENSMUST00000123058
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004871 signal transducer activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006805 xenobiotic metabolic process
GO:0007165 signal transduction
GO:0009410 response to xenobiotic stimulus
GO:0033235 positive regulation of protein sumoylation
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000063438
View Gene Order
ENSBTAG00000026527
Not yet available
Cross-References
SwissProt Q3U1U7
TrEMBL
UniProt Splice Variant
Entrez Gene 11624
UniGene Mm.290446
RefSeq NM_009644 XM_006517048 XM_006517049 XM_006517050 XM_006517051
OMIM
CCDS CCDS26641
HPRD
IMGT
MGI ID MGI:1333776
MGI Symbol Ahrr
EMBL AB015140 AC123833 AK154152 AK154761 AK155711 AK173134 BC118534 CT009486
GenPept AAI18535 BAA37132 BAD32412 BAE32410 BAE32810 BAE33396 CAO77884
RNA Seq Atlas 11624

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca