Version 5.4
Mus musculus Gene: Cyp4f18
Summary
InnateDB Gene IDBG-167298.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cyp4f18
Gene Name cytochrome P450, family 4, subfamily f, polypeptide 18
Synonyms 1810054N16Rik; Cyp4f3; Cypf18
Species Mus musculus
Ensembl Gene ENSMUSG00000003484
Encoded Proteins
IDBP-167300
cytochrome P450, family 4, subfamily f, polypeptide 18
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:71988482-72009626
Strand Reverse strand
Band B3.3
Transcripts
ENSMUST00000003574 ENSMUSP00000003574
ENSMUST00000141975
ENSMUST00000125448
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0050051 leukotriene-B4 20-monooxygenase activity
GO:0052871 alpha-tocopherol omega-hydroxylase activity
Biological Process
GO:0036101 leukotriene B4 catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_232159
Cytochrome P450 - arranged by substrate type pathway
REACT_263488
Eicosanoids pathway
REACT_249802
Phase 1 - Functionalization of compounds pathway
REACT_188937
Metabolism pathway
REACT_196572
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_216259
Miscellaneous substrates pathway
REACT_237452
Fatty acids pathway
REACT_232343
Biological oxidations pathway
REACT_188625
Arachidonic acid metabolism pathway
REACT_215561
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
KEGG
mmu00590
Arachidonic acid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q99N16
TrEMBL
UniProt Splice Variant
Entrez Gene 72054
UniGene Mm.160020
RefSeq NM_024444 XM_006509748
OMIM
CCDS CCDS22406
HPRD
IMGT
MGI ID MGI:1919304
MGI Symbol Cyp4f18
EMBL AC162522 AF233647 AK007863 BC013494
GenPept AAH13494 AAK15013 BAB25315
RNA Seq Atlas 72054

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca