Version 5.4
| Mus musculus Gene: Sumo3 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-167402.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | Sumo3 | ||||||||||||||||||
| Gene Name | SMT3 suppressor of mif two 3 homolog 3 (yeast) | ||||||||||||||||||
| Synonyms | 2810014B19Rik; D10Ertd345e; SMT3A; Smt3h1; SUMO-3 | ||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||
| Ensembl Gene | ENSMUSG00000020265 | ||||||||||||||||||
| Encoded Proteins |
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (yeast)
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a member of the small ubiquitin-like modifier family. The encoded protein may regulate a variety of proteins in many pathways via a post-translational modification, known as SUMOylation. This activity may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, mitosis, transcriptional regulation, and signal transduction. Disruption of some of these processes has been associated with cerebral ischemia, neural dysfunction, and heart disease. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 10:77606097-77641543 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | C1 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
SUMO is conjugated to E1 (UBA2:SAE1) pathway
SUMO is proteolytically processed pathway
SUMOylation pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
SUMO is transferred from E1 to E2 (UBE2I, UBC9) pathway
Processing and activation of SUMO pathway
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| KEGG |
RNA transport pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | G3UWI9 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 20610 | ||||||||||||||||||
| UniGene | Mm.24433 Mm.464798 | ||||||||||||||||||
| RefSeq | NM_019929 XM_006513426 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS23958 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| MGI ID | MGI:1336201 | ||||||||||||||||||
| MGI Symbol | Sumo3 | ||||||||||||||||||
| EMBL | AC153864 CH466553 | ||||||||||||||||||
| GenPept | EDL31801 | ||||||||||||||||||
| RNA Seq Atlas | 20610 | ||||||||||||||||||