Version 5.4
Mus musculus Gene: Tcf20
Summary
InnateDB Gene IDBG-167515.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tcf20
Gene Name transcription factor 20
Synonyms 2810438H08Rik; mKIAA0292; SPBP
Species Mus musculus
Ensembl Gene ENSMUSG00000041852
Encoded Proteins
IDBP-167519
transcription factor 20
IDBP-262240
transcription factor 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100207:
The protein encoded by this gene binds a platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 (stromelysin 1) promoter. The protein localizes to the nucleus and displays DNA-binding and transactivation activities. It is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:82808629-82912134
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000048966 ENSMUSP00000048486
ENSMUST00000109510 ENSMUSP00000105136
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100207
View Gene Order
ENSBTAG00000000662
Not yet available
Cross-References
SwissProt Q9EPQ8
TrEMBL Q80U46
UniProt Splice Variant
Entrez Gene 21411
UniGene Mm.252156
RefSeq NM_001114140 XM_006520728 XM_006520731 XM_006520732 XM_006520733 NM_013836 XM_006520730
OMIM
CCDS CCDS49681 CCDS27693
HPRD
IMGT
MGI ID MGI:108399
MGI Symbol Tcf20
EMBL AC087902 AC129563 AK122239 AY007594 BC138038 U20284
GenPept AAA86495 AAG28929 AAI38039 BAC65521
RNA Seq Atlas 21411

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca