Version 5.4
Mus musculus Gene: Chrnb4
Summary
InnateDB Gene IDBG-167569.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chrnb4
Gene Name cholinergic receptor, nicotinic, beta polypeptide 4
Synonyms Acrb-4; Acrb4
Species Mus musculus
Ensembl Gene ENSMUSG00000035200
Encoded Proteins
IDBP-167571
cholinergic receptor, nicotinic, beta polypeptide 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117971:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:55028156-55048544
Strand Reverse strand
Band B
Transcripts
ENSMUST00000034854 ENSMUSP00000034854
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004889 acetylcholine-activated cation-selective channel activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0015464 acetylcholine receptor activity
Biological Process
GO:0001508 action potential
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0006939 smooth muscle contraction
GO:0006940 regulation of smooth muscle contraction
GO:0007165 signal transduction
GO:0007626 locomotory behavior
GO:0034220 ion transmembrane transport
GO:0035094 response to nicotine
GO:0035095 behavioral response to nicotine
GO:0042391 regulation of membrane potential
GO:0060084 synaptic transmission involved in micturition
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000117971
View Gene Order
ENSBTAG00000003132
Not yet available
Pathways
NETPATH
REACTOME
REACT_203664
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_198591
Presynaptic nicotinic acetylcholine receptors pathway
REACT_198593
Highly sodium permeable acetylcholine nicotinic receptors pathway
REACT_259290
Neuronal System pathway
REACT_198589
Activation of Nicotinic Acetylcholine Receptors pathway
REACT_198583
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors pathway
REACT_198587
Acetylcholine Binding And Downstream Events pathway
REACT_198586
Postsynaptic nicotinic acetylcholine receptors pathway
REACT_198585
Highly calcium permeable nicotinic acetylcholine receptors pathway
REACT_233318
Transmission across Chemical Synapses pathway
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13685
Neuronal System pathway
REACT_22352
Highly calcium permeable nicotinic acetylcholine receptors pathway
REACT_22149
Postsynaptic nicotinic acetylcholine receptors pathway
REACT_22223
Highly sodium permeable acetylcholine nicotinic receptors pathway
REACT_22126
Activation of Nicotinic Acetylcholine Receptors pathway
REACT_22336
Presynaptic nicotinic acetylcholine receptors pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_22303
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
REACT_15461
Acetylcholine Binding And Downstream Events pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.404627
RefSeq NM_148944 XM_006510757
OMIM
CCDS CCDS23200
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca