InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: CHRNB4

Summary

InnateDB Gene

IDBG-25047.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHRNB4

Gene Name

cholinergic receptor, nicotinic, beta 4 (neuronal)

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000117971

Encoded Proteins

IDBP-25049

cholinergic receptor, nicotinic, beta 4

IDBP-378653

cholinergic receptor, nicotinic, beta 4

IDBP-747046

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:78624119-78727754

Strand

Reverse strand

Band

q25.1

Transcripts

ENST00000261751	ENSP00000261751
ENST00000412074	ENSP00000416386
ENST00000559849	ENSP00000457404
ENST00000560511

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004889	acetylcholine-activated cation-selective channel activity
GO:0005230	extracellular ligand-gated ion channel activity
GO:0015276	ligand-gated ion channel activity
GO:0015464	acetylcholine receptor activity

Biological Process

GO:0001508	action potential
GO:0006810	transport
GO:0006811	ion transport
GO:0006812	cation transport
GO:0006939	smooth muscle contraction
GO:0006940	regulation of smooth muscle contraction
GO:0007165	signal transduction
GO:0007268	synaptic transmission
GO:0007271	synaptic transmission, cholinergic
GO:0007626	locomotory behavior
GO:0034220	ion transmembrane transport
GO:0035094	response to nicotine
GO:0035095	behavioral response to nicotine
GO:0042391	regulation of membrane potential
GO:0046928	regulation of neurotransmitter secretion
GO:0060084	synaptic transmission involved in micturition

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0005892	acetylcholine-gated channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0045211	postsynaptic membrane