Version 5.4
Mus musculus Gene: Isl2
Summary
InnateDB Gene IDBG-168039.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Isl2
Gene Name insulin related protein 2 (islet 2)
Synonyms 3110001N10Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000032318
Encoded Proteins
IDBP-168041
insulin related protein 2 (islet 2)
IDBP-252096
insulin related protein 2 (islet 2)
IDBP-625399
insulin related protein 2 (islet 2)
IDBP-789895
insulin related protein 2 (islet 2)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159556:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:55538672-55546180
Strand Forward strand
Band B
Transcripts
ENSMUST00000034869 ENSMUSP00000034869
ENSMUST00000114290 ENSMUSP00000109929
ENSMUST00000164373 ENSMUSP00000130638
ENSMUST00000165302
ENSMUST00000175950 ENSMUSP00000139485
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0021520 spinal cord motor neuron cell fate specification
GO:0021524 visceral motor neuron differentiation
GO:0031290 retinal ganglion cell axon guidance
GO:0045665 negative regulation of neuron differentiation
GO:0048663 neuron fate commitment
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000159556
View Gene Order
ENSBTAG00000016651
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.273996
RefSeq NM_027397
OMIM
CCDS CCDS23205
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca