Version 5.4
Mus musculus Protein: Isl2
Summary
InnateDB Protein IDBP-625399.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Isl2
Protein Name insulin related protein 2 (islet 2)
Synonyms 3110001N10Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000130638
InnateDB Gene IDBG-168039 (Isl2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0021520 spinal cord motor neuron cell fate specification
GO:0021524 visceral motor neuron differentiation
GO:0031290 retinal ganglion cell axon guidance
GO:0045665 negative regulation of neuron differentiation
GO:0048663 neuron fate commitment
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID MGI:109156
InterPro IPR001781 Zinc finger, LIM-type
PFAM PF00412
PRINTS
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0VAX2
UniProt Splice Variant
Entrez Gene 104360
UniGene Mm.273996
RefSeq
MGI ID
MGI Symbol Isl2
OMIM
CCDS
HPRD
IMGT
EMBL AC116699 BC120880 BC148307
GenPept AAI20881 AAI48308

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca