Version 5.4
Mus musculus Gene: Rps6ka6
Summary
InnateDB Gene IDBG-168288.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rps6ka6
Gene Name ribosomal protein S6 kinase polypeptide 6
Synonyms 2610524K04Rik; RSK4; S6K-alpha-6
Species Mus musculus
Ensembl Gene ENSMUSG00000025665
Encoded Proteins
IDBP-168290
ribosomal protein S6 kinase polypeptide 6
IDBP-168292
ribosomal protein S6 kinase polypeptide 6
IDBP-168294
ribosomal protein S6 kinase polypeptide 6
IDBP-253895
ribosomal protein S6 kinase polypeptide 6
IDBP-538885
ribosomal protein S6 kinase polypeptide 6
IDBP-537397
ribosomal protein S6 kinase polypeptide 6
IDBP-537498
ribosomal protein S6 kinase polypeptide 6
IDBP-542332
ribosomal protein S6 kinase polypeptide 6
IDBP-533990
ribosomal protein S6 kinase polypeptide 6
IDBP-540700
ribosomal protein S6 kinase polypeptide 6
IDBP-535703
ribosomal protein S6 kinase polypeptide 6
IDBP-541219
ribosomal protein S6 kinase polypeptide 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072133:
This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:111388192-111537959
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000096348 ENSMUSP00000094073
ENSMUST00000065976 ENSMUSP00000068483
ENSMUST00000082034 ENSMUSP00000080694
ENSMUST00000113428 ENSMUSP00000109055
ENSMUST00000137712 ENSMUSP00000121722
ENSMUST00000138645 ENSMUSP00000121489
ENSMUST00000123213 ENSMUSP00000118075
ENSMUST00000128819 ENSMUSP00000117228
ENSMUST00000123102 ENSMUSP00000120004
ENSMUST00000132319 ENSMUSP00000120611
ENSMUST00000123951 ENSMUSP00000115975
ENSMUST00000156639 ENSMUSP00000121075
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0035556 intracellular signal transduction
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000072133
View Gene Order
ENSBTAG00000002015
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04010
MAPK signaling pathway pathway
mmu04720
Long-term potentiation pathway
mmu04150
mTOR signaling pathway pathway
mmu04722
Neurotrophin signaling pathway pathway
mmu04914
Progesterone-mediated oocyte maturation pathway
mmu04114
Oocyte meiosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20510
RSK activation pathway
REACT_20568
CREB phosphorylation through the activation of Ras pathway
REACT_22365
Recycling pathway of L1 pathway
REACT_22205
L1CAM interactions pathway
REACT_111045
Developmental Biology pathway
REACT_13685
Neuronal System pathway
REACT_18266
Axon guidance pathway
REACT_20593
Post NMDA receptor activation events pathway
REACT_20563
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
REACT_13477
Transmission across Chemical Synapses pathway
REACT_15370
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
KEGG
hsa04150
mTOR signaling pathway pathway
hsa04010
MAPK signaling pathway pathway
hsa04720
Long-term potentiation pathway
hsa04722
Neurotrophin signaling pathway pathway
hsa04914
Progesterone-mediated oocyte maturation pathway
hsa04114
Oocyte meiosis pathway
INOH
INOH website
IL-7 signaling pathway
INOH website
JAK STAT pathway and regulation pathway
INOH website
EPO signaling pathway pathway
INOH website
VEGF signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.37617 Mm.400303 Mm.408313 Mm.488714
RefSeq NM_025949 XM_006528400 XM_006528401 XM_006528402 XM_006528403 XM_006528404
OMIM
CCDS CCDS30356
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca