Version 5.4
Mus musculus Gene: Grxcr1
Summary
InnateDB Gene IDBG-168349.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Grxcr1
Gene Name glutaredoxin, cysteine rich 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000068082
Encoded Proteins
IDBP-168351
glutaredoxin, cysteine rich 1
IDBP-628320
glutaredoxin, cysteine rich 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000215203:
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:68031835-68166398
Strand Forward strand
Band C3.1
Transcripts
ENSMUST00000094715 ENSMUSP00000092305
ENSMUST00000172955 ENSMUSP00000134114
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity
Biological Process
GO:0007605 sensory perception of sound
GO:0010923 negative regulation of phosphatase activity
GO:0042491 auditory receptor cell differentiation
GO:0045454 cell redox homeostasis
GO:0048563 post-embryonic organ morphogenesis
GO:0048839 inner ear development
GO:0055114 oxidation-reduction process
GO:0060118 vestibular receptor cell development
GO:0060119 inner ear receptor cell development
GO:0060122 inner ear receptor stereocilium organization
Cellular Component
GO:0032420 stereocilium
GO:0060091 kinocilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000215203
View Gene Order
ENSBTAG00000032947
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 433899
UniGene Mm.332422
RefSeq NM_001018019
OMIM
CCDS CCDS19319
HPRD
IMGT
MGI ID MGI:3577767
MGI Symbol Grxcr1
EMBL
GenPept
RNA Seq Atlas 433899

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca