Version 5.4
Mus musculus Gene: Ltc4s
Summary
InnateDB Gene IDBG-168449.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ltc4s
Gene Name leukotriene C4 synthase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020377
Encoded Proteins
IDBP-168451
leukotriene C4 synthase
IDBP-168453
leukotriene C4 synthase
IDBP-531850
leukotriene C4 synthase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:50236469-50238616
Strand Reverse strand
Band B1.3
Transcripts
ENSMUST00000101265 ENSMUSP00000098823
ENSMUST00000102772 ENSMUSP00000099833
ENSMUST00000125555 ENSMUSP00000121584
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004364 glutathione transferase activity
GO:0004464 leukotriene-C4 synthase activity
GO:0004602 glutathione peroxidase activity
GO:0005515 protein binding
GO:0008047 enzyme activator activity
GO:0008289 lipid binding
Biological Process
GO:0006691 leukotriene metabolic process
GO:0019370 leukotriene biosynthetic process
GO:0043085 positive regulation of catalytic activity
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005635 nuclear envelope
GO:0005640 nuclear outer membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_196544
Synthesis of Lipoxins (LX) pathway
REACT_206751
Synthesis of 5-eicosatetraenoic acids pathway
REACT_188625
Arachidonic acid metabolism pathway
REACT_215561
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
KEGG
mmu00590
Arachidonic acid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.245151
RefSeq NM_008521 XM_006532356
OMIM
CCDS CCDS24631
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca