InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: NUPL1

Summary

InnateDB Gene

IDBG-16856.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUPL1

Gene Name

nucleoporin like 1

Synonyms

PRO2463

Species

Homo sapiens

Ensembl Gene

ENSG00000139496

Encoded Proteins

IDBP-16858

nucleoporin like 1

IDBP-16862

nucleoporin like 1

IDBP-16868

nucleoporin like 1

IDBP-362246

nucleoporin like 1

IDBP-476412

nucleoporin like 1

IDBP-476237

nucleoporin like 1

IDBP-478086

nucleoporin like 1

IDBP-478466

nucleoporin like 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
This gene encodes a member of the nucleoporin family that shares 87%% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:25301524-25349800

Strand

Forward strand

Band

q12.13

Transcripts

ENST00000381747	ENSP00000371166
ENST00000381736	ENSP00000371155
ENST00000381718	ENSP00000371137
ENST00000394327	ENSP00000408147
ENST00000481980	ENSP00000418341
ENST00000490231	ENSP00000418244
ENST00000480187
ENST00000460326
ENST00000465068	ENSP00000418904
ENST00000466694
ENST00000463407	ENSP00000418555
ENST00000495460
ENST00000476553
ENST00000477876

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005487	nucleocytoplasmic transporter activity
GO:0005515	protein binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0005975	carbohydrate metabolic process
GO:0006913	nucleocytoplasmic transport
GO:0007077	mitotic nuclear envelope disassembly
GO:0008645	hexose transport
GO:0010827	regulation of glucose transport
GO:0015031	protein transport
GO:0015758	glucose transport
GO:0016032	viral process
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0051028	mRNA transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005635	nuclear envelope
GO:0005643	nuclear pore
GO:0031965	nuclear membrane

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000063895

View Gene Order

ENSBTAG00000015225

Not yet available

Pathways

NETPATH

REACTOME

KEGG

hsa03013

RNA transport pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.566317 Hs.594723 Hs.741412

RefSeq

NM_001008564 NM_014089

HUGO

OMIM

CCDS

CCDS31949 CCDS9314

HPRD

06355

IMGT

EMBL

GenPept

RNA Seq Atlas