Version 5.4
Mus musculus Gene: Gnpda2
Summary
InnateDB Gene IDBG-168742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gnpda2
Gene Name glucosamine-6-phosphate deaminase 2
Synonyms 4921523I18Rik; 4933412A11Rik; BB189630; Gnp2; GNPDA; mKIAA4008; Sb52
Species Mus musculus
Ensembl Gene ENSMUSG00000029209
Encoded Proteins
IDBP-168746
glucosamine-6-phosphate deaminase 2
IDBP-400877
glucosamine-6-phosphate deaminase 2
IDBP-531930
glucosamine-6-phosphate deaminase 2
IDBP-539853
glucosamine-6-phosphate deaminase 2
IDBP-628337
glucosamine-6-phosphate deaminase 2
IDBP-628338
glucosamine-6-phosphate deaminase 2
IDBP-628339
glucosamine-6-phosphate deaminase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163281:
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:69573108-69592337
Strand Reverse strand
Band C3.1
Transcripts
ENSMUST00000031117 ENSMUSP00000031117
ENSMUST00000120789 ENSMUSP00000112484
ENSMUST00000139632 ENSMUSP00000121014
ENSMUST00000154018
ENSMUST00000145775
ENSMUST00000144203
ENSMUST00000153536 ENSMUSP00000121441
ENSMUST00000173927 ENSMUSP00000133490
ENSMUST00000174233 ENSMUSP00000133670
ENSMUST00000166298 ENSMUSP00000128233
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004342 glucosamine-6-phosphate deaminase activity
GO:0016787 hydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006044 N-acetylglucosamine metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163281
View Gene Order
ENSBTAG00000000287
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.33830
RefSeq NM_001038015 XM_006504072 XM_006504073 XM_006504074
OMIM
CCDS CCDS19324
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca