Version 5.4
Bos taurus Gene: GNPDA2
Summary
InnateDB Gene IDBG-641971.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GNPDA2
Gene Name Glucosamine-6-phosphate isomerase 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000287
Encoded Proteins
IDBP-694382
Glucosamine-6-phosphate isomerase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163281:
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:64961798-64992219
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000357 ENSBTAP00000000357
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004342 glucosamine-6-phosphate deaminase activity
GO:0016787 hydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006044 N-acetylglucosamine metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163281
View Gene Order
ENSMUSG00000029209
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
mmu00520
Amino sugar and nucleotide sugar metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q17QL1
TrEMBL
UniProt Splice Variant
Entrez Gene 508383
UniGene Bt.20629
RefSeq NM_001075356 XM_005207916 XM_005207918
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118295
GenPept AAI18296
RNA Seq Atlas 508383

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca