Version 5.4
Mus musculus Gene: Efcab6
Summary
InnateDB Gene IDBG-168808.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Efcab6
Gene Name EF-hand calcium binding domain 6
Synonyms 4931407K02Rik; 4932408N08Rik; bM150J22.2; mKIAA1672
Species Mus musculus
Ensembl Gene ENSMUSG00000022441
Encoded Proteins
IDBP-538209
EF-hand calcium binding domain 6
IDBP-623639
EF-hand calcium binding domain 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186976:
This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:83866712-84065379
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000156187 ENSMUSP00000114909
ENSMUST00000144169
ENSMUST00000143592
ENSMUST00000130551
ENSMUST00000149563
ENSMUST00000140633
ENSMUST00000122836
ENSMUST00000163773 ENSMUSP00000128002
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186976
View Gene Order
ENSBTAG00000030189
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.196288
RefSeq NM_001161628 NM_001161629 NM_029946 XM_006521531 XM_006521533 XM_006521536
OMIM
CCDS CCDS27707
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca