Version 5.4
Mus musculus Protein: Efcab6
Summary
InnateDB Protein IDBP-538209.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Efcab6
Protein Name EF-hand calcium binding domain 6
Synonyms 4931407K02Rik; 4932408N08Rik; bM150J22.2; mKIAA1672;
Species Mus musculus
Ensembl Protein ENSMUSP00000114909
InnateDB Gene IDBG-168808 (Efcab6)
Protein Structure
UniProt Annotation
Function Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1924877
InterPro IPR002048 EF-hand domain
IPR015070 EF-hand calcium-binding domain-containing protein 6
PFAM PF00036
PF13202
PF13405
PF08976
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P1E8
PhosphoSite PhosphoSite-Q6P1E8
TrEMBL
UniProt Splice Variant
Entrez Gene 77627
UniGene Mm.196288
RefSeq NP_084222
MGI ID
MGI Symbol Efcab6
OMIM
CCDS CCDS27707
HPRD
IMGT
EMBL AK019850 AK220412 AL513354 AL603867 BC056955 BC065111
GenPept AAH56955 AAH65111 BAB31880 BAD90458 CAO77882 CAO78062 CAO78063 CAO78064

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca