Version 5.4
Mus musculus Gene: Gpr98
Summary
InnateDB Gene IDBG-169620.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr98
Gene Name G protein-coupled receptor 98
Synonyms Frings; Mass1; Mgr1; VLGR1
Species Mus musculus
Ensembl Gene ENSMUSG00000069170
Encoded Proteins
IDBP-169622
G protein-coupled receptor 98
IDBP-262107
G protein-coupled receptor 98
IDBP-541930
G protein-coupled receptor 98
IDBP-535688
G protein-coupled receptor 98
IDBP-536444
G protein-coupled receptor 98
IDBP-538298
G protein-coupled receptor 98
IDBP-531676
G protein-coupled receptor 98
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164199:
This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:81095068-81633154
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000095585 ENSMUSP00000093245
ENSMUST00000109565 ENSMUSP00000105193
ENSMUST00000128120 ENSMUSP00000122358
ENSMUST00000125698 ENSMUSP00000120136
ENSMUST00000156631
ENSMUST00000156627
ENSMUST00000129725
ENSMUST00000146141
ENSMUST00000125663
ENSMUST00000126444 ENSMUSP00000123552
ENSMUST00000128585 ENSMUSP00000121899
ENSMUST00000146749 ENSMUSP00000114579
ENSMUST00000132045
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0017022 myosin binding
Biological Process
GO:0007154 cell communication
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007399 nervous system development
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0016337 single organismal cell-cell adhesion
GO:0045494 photoreceptor cell maintenance
GO:0048496 maintenance of organ identity
GO:0048839 inner ear development
GO:0050877 neurological system process
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0050953 sensory perception of light stimulus
GO:0060122 inner ear receptor stereocilium organization
Cellular Component
GO:0002142 stereocilia ankle link complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164199
View Gene Order
ENSBTAG00000006031
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 110789
UniGene Mm.288694
RefSeq NM_054053 XM_006517045 XM_006517046 XM_006517047
OMIM
CCDS CCDS36737
HPRD
IMGT
MGI ID MGI:1274784
MGI Symbol Gpr98
EMBL
GenPept
RNA Seq Atlas 110789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca