Version 5.4
Mus musculus Gene: Prodh2
Summary
InnateDB Gene IDBG-169628.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prodh2
Gene Name proline dehydrogenase (oxidase) 2
Synonyms 2510028N04Rik; 2510038B11Rik; MmPOX; MmPOX1; POX1
Species Mus musculus
Ensembl Gene ENSMUSG00000036892
Encoded Proteins
IDBP-169630
proline dehydrogenase (oxidase) 2
IDBP-534244
proline dehydrogenase (oxidase) 2
IDBP-532721
proline dehydrogenase (oxidase) 2
IDBP-538962
proline dehydrogenase (oxidase) 2
IDBP-540976
proline dehydrogenase (oxidase) 2
IDBP-533296
proline dehydrogenase (oxidase) 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000250799:
The protein encoded by this gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme which catalyzes the first step in proline catabolism. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:30493622-30513402
Strand Forward strand
Band B1
Transcripts
ENSMUST00000058280 ENSMUSP00000062214
ENSMUST00000142514
ENSMUST00000133318 ENSMUSP00000122546
ENSMUST00000142575 ENSMUSP00000114778
ENSMUST00000131789
ENSMUST00000130839 ENSMUSP00000117480
ENSMUST00000131040 ENSMUSP00000116662
ENSMUST00000122876 ENSMUSP00000114278
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004657 proline dehydrogenase activity
Biological Process
GO:0006537 glutamate biosynthetic process
GO:0006562 proline catabolic process
GO:0010133 proline catabolic process to glutamate
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000250799
View Gene Order
ENSBTAG00000031772
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00330
Arginine and proline metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00330
Arginine and proline metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.270525
RefSeq NM_019546 XM_006540223 XM_006540224
OMIM
CCDS CCDS21093
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca