Version 5.4
Homo sapiens Gene: PRODH2
Summary
InnateDB Gene IDBG-409322.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRODH2
Gene Name proline dehydrogenase (oxidase) 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000250799
Encoded Proteins
IDBP-45500
proline dehydrogenase (oxidase) 2
IDBP-762234
IDBP-813350
proline dehydrogenase (oxidase) 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme which catalyzes the first step in proline catabolism. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35799988-35813299
Strand Reverse strand
Band q13.12
Transcripts
ENST00000301175 ENSP00000301175
ENST00000587808
ENST00000588266 ENSP00000465214
ENST00000587695
ENST00000591694
ENST00000589835 ENSP00000474199
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004657 proline dehydrogenase activity
Biological Process
GO:0006537 glutamate biosynthetic process
GO:0006562 proline catabolic process
GO:0010133 proline catabolic process to glutamate
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036892
View Gene Order
ENSBTAG00000031772
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00330
Arginine and proline metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_021232
HUGO
OMIM
CCDS CCDS12478
HPRD 17911
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca