Version 5.4
Mus musculus Gene: Arhgap33
Summary
InnateDB Gene IDBG-169820.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap33
Gene Name Rho GTPase activating protein 33
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000036882
Encoded Proteins
IDBP-169822
Rho GTPase activating protein 33
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000004777:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:30522226-30534180
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000044338 ENSMUSP00000038412
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
GO:0030675 Rac GTPase activator activity
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0007165 signal transduction
GO:0015031 protein transport
GO:0032321 positive regulation of Rho GTPase activity
GO:0032855 positive regulation of Rac GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000004777
View Gene Order
ENSBTAG00000009714
Not yet available
Pathways
NETPATH
REACTOME
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q80YF9
TrEMBL
UniProt Splice Variant
Entrez Gene 233071
UniGene Mm.190704
RefSeq NM_001289670 NM_001289682 NM_178252 XM_006539886 XM_006539888 XM_006539889
OMIM
CCDS CCDS21095
HPRD
IMGT
MGI ID MGI:2673998
MGI Symbol Arhgap33
EMBL AY217764 BC061471 BC065086 BC065166 BC066047
GenPept AAH61471 AAH65086 AAH65166 AAH66047 AAO89073
RNA Seq Atlas 233071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca