Version 5.4
Homo sapiens Gene: RIN3
Summary
InnateDB Gene IDBG-17044.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIN3
Gene Name Ras and Rab interactor 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100599
Encoded Proteins
IDBP-17046
Ras and Rab interactor 3
IDBP-587337
Ras and Rab interactor 3
IDBP-592252
Ras and Rab interactor 3
IDBP-584402
Ras and Rab interactor 3
IDBP-808477
Ras and Rab interactor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary RIN3 is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases (see RAB5A; MIM 179512) (Kajiho et al., 2003 [PubMed 12972505]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:92513774-92688994
Strand Forward strand
Band q32.12
Transcripts
ENST00000216487 ENSP00000216487
ENST00000418924
ENST00000555589 ENSP00000450682
ENST00000557762 ENSP00000452155
ENST00000556385
ENST00000555908
ENST00000555891
ENST00000554888
ENST00000553992
ENST00000556418 ENSP00000450986
ENST00000553959
ENST00000620541 ENSP00000480603
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0017112 Rab guanyl-nucleotide exchange factor activity
GO:0017137 Rab GTPase binding
Biological Process
GO:0006897 endocytosis
GO:0007165 signal transduction
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
GO:0005769 early endosome
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044456
View Gene Order
ENSBTAG00000010416
Not yet available
Cross-References
SwissProt
TrEMBL G3V2I7
UniProt Splice Variant
Entrez Gene 79890
UniGene
RefSeq NM_024832
HUGO HGNC:18751
OMIM 610223
CCDS CCDS32144
HPRD 11494
IMGT
EMBL AL136332 AL159141 CH471061
GenPept EAW81494
RNA Seq Atlas 79890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca