Version 5.4
Mus musculus Gene: Acot11
Summary
InnateDB Gene IDBG-170686.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acot11
Gene Name acyl-CoA thioesterase 11
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034853
Encoded Proteins
IDBP-170688
acyl-CoA thioesterase 11
IDBP-170690
acyl-CoA thioesterase 11
IDBP-532419
acyl-CoA thioesterase 11
IDBP-539501
acyl-CoA thioesterase 11
IDBP-532379
acyl-CoA thioesterase 11
IDBP-535915
acyl-CoA thioesterase 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162390:
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:106744555-106804998
Strand Reverse strand
Band C7
Transcripts
ENSMUST00000102762 ENSMUSP00000099823
ENSMUST00000065253 ENSMUSP00000069636
ENSMUST00000140541 ENSMUSP00000124567
ENSMUST00000144809
ENSMUST00000156567 ENSMUSP00000123942
ENSMUST00000145061 ENSMUSP00000125123
ENSMUST00000148688 ENSMUSP00000124385
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
GO:0047617 acyl-CoA hydrolase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0009266 response to temperature stimulus
GO:0009409 response to cold
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000162390
View Gene Order
ENSBTAG00000039686
Not yet available
Cross-References
SwissProt
TrEMBL A2AVR6 E0CXP8 E0CYA0 Q3TBG4 Q80TT9 Q8CAL6
UniProt Splice Variant
Entrez Gene 329910
UniGene Mm.222956 Mm.448842
RefSeq XM_006503181 NM_025590 XM_006503182
OMIM
CCDS CCDS18426
HPRD
IMGT
MGI ID MGI:1913736
MGI Symbol Acot11
EMBL AK038546 AK122350 AK170189 AK171255 AL929585
GenPept BAC30036 BAC65632 BAE41624 BAE42347
RNA Seq Atlas 329910

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca