Version 5.4
Mus musculus Gene: Cdkl3
Summary
InnateDB Gene IDBG-170741.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdkl3
Gene Name cyclin-dependent kinase-like 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020389
Encoded Proteins
IDBP-170743
cyclin-dependent kinase-like 3
IDBP-170745
cyclin-dependent kinase-like 3
IDBP-263145
cyclin-dependent kinase-like 3
IDBP-263147
cyclin-dependent kinase-like 3
IDBP-263149
cyclin-dependent kinase-like 3
IDBP-263151
cyclin-dependent kinase-like 3
IDBP-263153
cyclin-dependent kinase-like 3
IDBP-263155
cyclin-dependent kinase-like 3
IDBP-400606
cyclin-dependent kinase-like 3
IDBP-400607
cyclin-dependent kinase-like 3
IDBP-533619
cyclin-dependent kinase-like 3
IDBP-540696
cyclin-dependent kinase-like 3
IDBP-539640
cyclin-dependent kinase-like 3
IDBP-540751
cyclin-dependent kinase-like 3
IDBP-540742
cyclin-dependent kinase-like 3
IDBP-542142
cyclin-dependent kinase-like 3
IDBP-533213
cyclin-dependent kinase-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006837:
The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:52004221-52089784
Strand Forward strand
Band B1.3
Transcripts
ENSMUST00000063321 ENSMUSP00000065128
ENSMUST00000063303 ENSMUSP00000064315
ENSMUST00000109081 ENSMUSP00000104709
ENSMUST00000109080 ENSMUSP00000104708
ENSMUST00000109079 ENSMUSP00000104707
ENSMUST00000109078 ENSMUSP00000104706
ENSMUST00000109077 ENSMUSP00000104705
ENSMUST00000109076 ENSMUSP00000104704
ENSMUST00000121591 ENSMUSP00000112477
ENSMUST00000120374 ENSMUSP00000113303
ENSMUST00000135076 ENSMUSP00000117983
ENSMUST00000143228 ENSMUSP00000123279
ENSMUST00000128853 ENSMUSP00000121945
ENSMUST00000147874 ENSMUSP00000119505
ENSMUST00000150736 ENSMUSP00000118607
ENSMUST00000154701 ENSMUSP00000116009
ENSMUST00000136021 ENSMUSP00000117315
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007049 cell cycle
GO:0030517 negative regulation of axon extension
GO:0050775 positive regulation of dendrite morphogenesis
GO:0097484 dendrite extension
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000006837
View Gene Order
ENSBTAG00000010979
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.280557 Mm.399289 Mm.487621
RefSeq NM_001166653 NM_001166654 NM_001166655 NM_001166656 NM_001166657 NM_153785 XM_006532775 XM_006532777 XM_006532778
OMIM
CCDS CCDS24665 CCDS48788 CCDS48789 CCDS48790 CCDS48791 CCDS48792
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca