InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gbe1

Summary

InnateDB Gene

IDBG-170927.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gbe1

Gene Name

glucan (1,4-alpha-), branching enzyme 1

Synonyms

2310045H19Rik; 2810426P10Rik; D16Ertd536e

Species

Mus musculus

Ensembl Gene

ENSMUSG00000022707

Encoded Proteins

IDBP-170929

glucan (1,4-alpha-), branching enzyme 1

IDBP-624787

glucan (1,4-alpha-), branching enzyme 1

IDBP-624804

glucan (1,4-alpha-), branching enzyme 1

IDBP-624806

glucan (1,4-alpha-), branching enzyme 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114480:
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease). [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen\'s disease). [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:70313949-70569716

Strand

Forward strand

Band

Transcripts

ENSMUST00000023393	ENSMUSP00000023393
ENSMUST00000099628
ENSMUST00000163832	ENSMUSP00000132603
ENSMUST00000164300
ENSMUST00000169432
ENSMUST00000170464	ENSMUSP00000131320
ENSMUST00000171132	ENSMUSP00000127642

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003844	1,4-alpha-glucan branching enzyme activity
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0043169	cation binding