InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gbe1

Summary

InnateDB Protein

IDBP-624787.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gbe1

Protein Name

glucan (1,4-alpha-), branching enzyme 1

Synonyms

2310045H19Rik; 2810426P10Rik; D16Ertd536e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000132603

InnateDB Gene

IDBG-170927 (Gbe1)

Protein Structure

UniProt Annotation

Function

Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003844	1,4-alpha-glucan branching enzyme activity
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0043169	cation binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0005978	glycogen biosynthetic process

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1921435

InterPro

IPR004193 Glycoside hydrolase, family 13, N-terminal
IPR006047 Glycosyl hydrolase, family 13, catalytic domain
IPR006048 Alpha-amylase, C-terminal all beta
IPR006589 Glycosyl hydrolase, family 13, subfamily, catalytic domain
IPR014756 Immunoglobulin E-set
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF02922
PF00128
PF02806

PRINTS

PIRSF

SMART

SM00632
SM00642

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D6Y9