Version 5.4
Mus musculus Gene: Speg
Summary
InnateDB Gene IDBG-170969.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Speg
Gene Name SPEG complex locus
Synonyms Apeg1; AW125581; BPEG; D1Bwg1450e; mKIAA1297; SPEGalpha; SPEGbeta
Species Mus musculus
Ensembl Gene ENSMUSG00000026207
Encoded Proteins
IDBP-170973
SPEG complex locus
IDBP-253550
SPEG complex locus
IDBP-253552
SPEG complex locus
IDBP-253554
SPEG complex locus
IDBP-253556
SPEG complex locus
IDBP-401018
SPEG complex locus
IDBP-540659
SPEG complex locus
IDBP-532391
SPEG complex locus
IDBP-539254
SPEG complex locus
IDBP-790235
SPEG complex locus
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants that encode different protein isoforms have been defined. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:75375297-75432320
Strand Forward strand
Band C4
Transcripts
ENSMUST00000087122 ENSMUSP00000084361
ENSMUST00000113590 ENSMUSP00000109220
ENSMUST00000113589 ENSMUSP00000109219
ENSMUST00000113588 ENSMUSP00000109218
ENSMUST00000113587 ENSMUSP00000109217
ENSMUST00000122266 ENSMUSP00000113646
ENSMUST00000148515 ENSMUSP00000116953
ENSMUST00000125306 ENSMUSP00000119969
ENSMUST00000146705
ENSMUST00000125118
ENSMUST00000132228 ENSMUSP00000121825
ENSMUST00000132222
ENSMUST00000137868 ENSMUSP00000141009
ENSMUST00000143679
ENSMUST00000187214
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0001701 in utero embryonic development
GO:0006468 protein phosphorylation
GO:0042692 muscle cell differentiation
GO:0055013 cardiac muscle cell development
GO:0060541 respiratory system development
GO:0072358 cardiovascular system development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000072195
View Gene Order
ENSBTAG00000046176
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.275397 Mm.402617
RefSeq NM_001085370 NM_001085371 NM_001173477 NM_007463 XM_006496400 XM_006496401 XM_006496402 XM_006496404
OMIM
CCDS CCDS35626 CCDS48292 CCDS48293
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca