Version 5.4
Mus musculus Gene: Pi4kb
Summary
InnateDB Gene IDBG-171130.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pi4kb
Gene Name phosphatidylinositol 4-kinase, catalytic, beta polypeptide
Synonyms ESTM41; PI4K-beta; PI4Kbeta; Pik4cb
Species Mus musculus
Ensembl Gene ENSMUSG00000038861
Encoded Proteins
IDBP-171132
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
IDBP-267083
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
IDBP-541713
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
IDBP-540055
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
IDBP-535722
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
IDBP-621979
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143393:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:94974731-95006843
Strand Forward strand
Band F2.1
Transcripts
ENSMUST00000072287 ENSMUSP00000072134
ENSMUST00000107251 ENSMUSP00000102872
ENSMUST00000125476 ENSMUSP00000121965
ENSMUST00000138209 ENSMUSP00000119833
ENSMUST00000133297 ENSMUSP00000123529
ENSMUST00000133166
ENSMUST00000167008 ENSMUSP00000132150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004430 1-phosphatidylinositol 4-kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0046854 phosphatidylinositol phosphorylation
GO:0048015 phosphatidylinositol-mediated signaling
Cellular Component
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0030867 rough endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143393
View Gene Order
ENSBTAG00000007320
Not yet available
Pathways
NETPATH
REACTOME
REACT_198970
Synthesis of PIPs at the Golgi membrane pathway
REACT_199016
PI Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu04070
Phosphatidylinositol signaling system pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_120836
Synthesis of PIPs at the Golgi membrane pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121175
PI Metabolism pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
INOH
PID NCI
avb3_integrin_pathway
Integrins in angiogenesis
Cross-References
SwissProt
TrEMBL F6W459
UniProt Splice Variant
Entrez Gene 107650
UniGene
RefSeq NM_175356 XM_006500812 XM_006500813
OMIM
CCDS CCDS17599
HPRD
IMGT
MGI ID MGI:1334433
MGI Symbol Pi4kb
EMBL AC087062
GenPept
RNA Seq Atlas 107650

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca