Version 5.4
| Homo sapiens Gene: CLEC4D | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-17159.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | CLEC4D | ||||||||||||||||||
| Gene Name | C-type lectin domain family 4, member D | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000166527 | ||||||||||||||||||
| Encoded Proteins |
C-type lectin domain family 4, member D
C-type lectin domain family 4, member D
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| InnateDB Annotation | |||||||||||||||||||
| Summary |
CLEC4D and CLEC6A form a heterodimer complex which confers innate cells high ability to sense C. albicans infection by facilitating the activation of NFκB dependent inflammatory responses.
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| InnateDB Annotation from Orthologs | |||||||||||||||||||
| Summary |
[Mus musculus] Clec4d is an inducible myeloid-expressed C-type lectin receptor, whose expression is tightly linked to that of Clec4e.
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| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 12:8509475-8522366 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | p13.31 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||||||||||||
| SwissProt | Q8WXI8 | ||||||||||||||||||
| TrEMBL | A6NHA5 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 338339 | ||||||||||||||||||
| UniGene | Hs.351811 | ||||||||||||||||||
| RefSeq | NM_080387 | ||||||||||||||||||
| HUGO | HGNC:14554 | ||||||||||||||||||
| OMIM | 609964 | ||||||||||||||||||
| CCDS | CCDS8593 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC092746 AF411850 AY115592 AY297446 AY486482 AY486483 BC032313 | ||||||||||||||||||
| GenPept | AAH32313 AAL37713 AAM75389 AAQ63173 AAS59161 AAS59162 | ||||||||||||||||||
| RNA Seq Atlas | 338339 | ||||||||||||||||||