InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Dync1h1

Summary

InnateDB Gene

IDBG-171593.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dync1h1

Gene Name

dynein cytoplasmic 1 heavy chain 1

Synonyms

9930018I23Rik; AI894280; DHC1; DHC1a; Dnchc1; DNCL; Dnec1; Dnecl; Loa; MAP1C; mKIAA0325; P22; Swl

Species

Mus musculus

Ensembl Gene

ENSMUSG00000018707

Encoded Proteins

IDBP-171595

dynein cytoplasmic 1 heavy chain 1

IDBP-623103

dynein cytoplasmic 1 heavy chain 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197102:
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:110601452-110666945

Strand

Forward strand

Band

Transcripts

ENSMUST00000018851	ENSMUSP00000018851
ENSMUST00000107660
ENSMUST00000172218
ENSMUST00000167395	ENSMUSP00000126117
ENSMUST00000166185
ENSMUST00000171535
ENSMUST00000170024
ENSMUST00000166323

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 46 experimentally validated interaction(s) in this database.
They are also associated with 85 interaction(s) predicted by orthology.

Experimentally validated
Total	46 [view]
Protein-Protein	46 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	85 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0044822	poly(A) RNA binding
GO:0051959	dynein light intermediate chain binding

Biological Process

GO:0003341	cilium movement
GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0007018	microtubule-based movement
GO:0033962	cytoplasmic mRNA processing body assembly
GO:0034063	stress granule assembly

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005858	axonemal dynein complex
GO:0005874	microtubule
GO:0016020	membrane
GO:0030175	filopodium
GO:0030286	dynein complex
GO:0070062	extracellular vesicular exosome