InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: DYNC1H1

Summary

InnateDB Gene

IDBG-634680.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DYNC1H1

Gene Name

cytoplasmic dynein 1 heavy chain 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000016598

Encoded Proteins

IDBP-686902

dynein, cytoplasmic 1, heavy chain 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197102:
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 21:68507134-68568024

Strand

Forward strand

Band

Transcripts

ENSBTAT00000044652

ENSBTAP00000042130

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 95 interaction(s) predicted by orthology.

Predicted by orthology
Total	95 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0044822	poly(A) RNA binding
GO:0051959	dynein light intermediate chain binding

Biological Process

GO:0006200	ATP catabolic process
GO:0007018	microtubule-based movement
GO:0008152	metabolic process
GO:0033962	cytoplasmic mRNA processing body assembly
GO:0034063	stress granule assembly

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005874	microtubule
GO:0016020	membrane
GO:0030175	filopodium
GO:0030286	dynein complex
GO:0070062	extracellular vesicular exosome