Version 5.4
Homo sapiens Gene: PARP16
Summary
InnateDB Gene IDBG-17194.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PARP16
Gene Name poly (ADP-ribose) polymerase family, member 16
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138617
Encoded Proteins
IDBP-17198
poly (ADP-ribose) polymerase family, member 16
IDBP-375252
poly (ADP-ribose) polymerase family, member 16
IDBP-745085
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:65234460-65300618
Strand Reverse strand
Band q22.31
Transcripts
ENST00000261888 ENSP00000261888
ENST00000444347 ENSP00000396118
ENST00000559805 ENSP00000457982
ENST00000560149
ENST00000558873
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0019900 kinase binding
GO:0043539 protein serine/threonine kinase activator activity
Biological Process
GO:0006471 protein ADP-ribosylation
GO:0006987 activation of signaling protein activity involved in unfolded protein response
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0060548 negative regulation of cell death
GO:0070213 protein auto-ADP-ribosylation
GO:0071902 positive regulation of protein serine/threonine kinase activity
Cellular Component
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0071782 endoplasmic reticulum tubular network
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032392
View Gene Order
ENSBTAG00000012352
Not yet available
Cross-References
SwissProt Q8N5Y8
TrEMBL A0A024R5Y7
UniProt Splice Variant
Entrez Gene 54956
UniGene Hs.30634 Hs.614133 Hs.618971
RefSeq NM_017851 XM_005254516 XM_006720589 XM_006720590
HUGO HGNC:26040
OMIM
CCDS CCDS10204
HPRD 07919
IMGT
EMBL AK000516 BC006389 BC031074 CH471082
GenPept AAH06389 AAH31074 BAA91222 EAW77718 EAW77720
RNA Seq Atlas 54956

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca