Mus musculus Gene: Fxyd1
Summary
InnateDB Gene IDBG-172097.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fxyd1
Gene Name FXYD domain-containing ion transport regulator 1
Synonyms 0610012C17Rik; 1110006M24Rik; Plm; Pml
Species Mus musculus
Ensembl Gene ENSMUSG00000036570
Encoded Proteins
FXYD domain-containing ion transport regulator 1
FXYD domain-containing ion transport regulator 1
FXYD domain-containing ion transport regulator 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:31051681-31055656
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000039909 ENSMUSP00000048460
ENSMUST00000071697 ENSMUSP00000071617
ENSMUST00000108110 ENSMUSP00000103745
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005254 chloride channel activity
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006936 muscle contraction
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0034707 chloride channel complex
Orthologs
Species
Bos taurus
Homo sapiens
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
Ion transport by P-type ATPases pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_019503 NM_052991 NM_052992 NM_194321 XM_006540218
OMIM
CCDS CCDS21123
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas