InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fxyd1

Summary

InnateDB Protein

IDBP-172099.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fxyd1

Protein Name

FXYD domain-containing ion transport regulator 1

Synonyms

0610012C17Rik; 1110006M24Rik; Plm; Pml;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048460

InnateDB Gene

IDBG-172097 (Fxyd1)

Protein Structure

UniProt Annotation

Function

May have a functional role in muscle contraction. Induces a hyperpolarization-activated chloride current when exogenously expressed (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005254	chloride channel activity
GO:0005515	protein binding

Biological Process

GO:0006811	ion transport
GO:0006874	cellular calcium ion homeostasis
GO:0006936	muscle contraction
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0034707	chloride channel complex

Protein Structure and Domains

PDB ID

MGI:1889273

InterPro

IPR000272 Ion-transport regulator, FXYD motif

PFAM

PF02038

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Z239

PhosphoSite

PhosphoSite-Q9Z239

TrEMBL

UniProt Splice Variant

Entrez Gene

56188

UniGene

RefSeq

NP_443718

MGI ID

MGI Symbol

Fxyd1

OMIM

CCDS

CCDS21123

HPRD

IMGT

EMBL

AF089734 AF091390 AK002585 BC024671

GenPept

AAD11781 AAD41683 AAH24671 BAB22208