Version 5.4
Mus musculus Gene: Homer1
Summary
InnateDB Gene IDBG-172658.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Homer1
Gene Name homer homolog 1 (Drosophila)
Synonyms homer-1; PSD-Zip45; SYN47; Ves-1; vesl-1
Species Mus musculus
Ensembl Gene ENSMUSG00000007617
Encoded Proteins
IDBP-172660
homer homolog 1 (Drosophila)
IDBP-172662
homer homolog 1 (Drosophila)
IDBP-172664
homer homolog 1 (Drosophila)
IDBP-172666
homer homolog 1 (Drosophila)
IDBP-262263
homer homolog 1 (Drosophila)
IDBP-262265
homer homolog 1 (Drosophila)
IDBP-262267
homer homolog 1 (Drosophila)
IDBP-262269
homer homolog 1 (Drosophila)
IDBP-262271
homer homolog 1 (Drosophila)
IDBP-262273
homer homolog 1 (Drosophila)
IDBP-262275
homer homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152413:
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:93303757-93404129
Strand Forward strand
Band C3
Transcripts
ENSMUST00000102752 ENSMUSP00000099813
ENSMUST00000080127 ENSMUSP00000079026
ENSMUST00000060490 ENSMUSP00000050471
ENSMUST00000079086 ENSMUSP00000078093
ENSMUST00000109498 ENSMUSP00000105124
ENSMUST00000109497 ENSMUSP00000105123
ENSMUST00000109496 ENSMUSP00000105122
ENSMUST00000109495 ENSMUSP00000105121
ENSMUST00000109494 ENSMUSP00000105120
ENSMUST00000109493 ENSMUSP00000105119
ENSMUST00000109492 ENSMUSP00000105118
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0031802 type 5 metabotropic glutamate receptor binding
GO:0032947 protein complex scaffold
GO:0035256 G-protein coupled glutamate receptor binding
GO:0042802 identical protein binding
GO:0044325 ion channel binding
GO:0046982 protein heterodimerization activity
GO:0097110 scaffold protein binding
Biological Process
GO:0003009 skeletal muscle contraction
GO:0007216 G-protein coupled glutamate receptor signaling pathway
GO:0007623 circadian rhythm
GO:0035094 response to nicotine
GO:0035418 protein localization to synapse
GO:0042220 response to cocaine
GO:0048148 behavioral response to cocaine
GO:0048741 skeletal muscle fiber development
GO:0048875 chemical homeostasis within a tissue
GO:0051592 response to calcium ion
GO:0051928 positive regulation of calcium ion transport
GO:0090279 regulation of calcium ion import
GO:2001256 regulation of store-operated calcium entry
GO:2001257 regulation of cation channel activity
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030018 Z disc
GO:0030054 cell junction
GO:0030424 axon
GO:0030425 dendrite
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043034 costamere
GO:0043198 dendritic shaft
GO:0045177 apical part of cell
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0060076 excitatory synapse
GO:0097481 neuronal postsynaptic density
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000152413
View Gene Order
ENSBTAG00000025853
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.37533 Mm.405586 Mm.411113 Mm.443892 Mm.487548
RefSeq NM_001284189 NM_011982 NM_147176 NM_152134
OMIM
CCDS CCDS26687 CCDS36745 CCDS36746 CCDS70484
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca