Version 5.4
Mus musculus Gene: C4b
Summary
InnateDB Gene IDBG-173022.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C4b
Gene Name complement component 4B (Chido blood group)
Synonyms C4; Ss
Species Mus musculus
Ensembl Gene ENSMUSG00000073418
Encoded Proteins
IDBP-173024
complement component 4B (Childo blood group)
IDBP-627647
complement component 4B (Childo blood group)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:34728380-34743882
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000069507 ENSMUSP00000069418
ENSMUST00000173669
ENSMUST00000173057 ENSMUSP00000134611
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004866 endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0006954 inflammatory response
GO:0006958 complement activation, classical pathway
GO:0010951 negative regulation of endopeptidase activity
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_208792
Complement cascade pathway
REACT_198562
Regulation of Complement cascade pathway
REACT_230745
Immune System pathway
REACT_202834
Initial triggering of complement pathway
REACT_213087
Activation of C3 and C5 pathway
KEGG
mmu04610
Complement and coagulation cascades pathway
mmu05322
Systemic lupus erythematosus pathway
mmu05150
Staphylococcus aureus infection pathway
INOH
PID NCI
Cross-References
SwissProt P01029
TrEMBL B0G0Y3 Q3TYN1 Q9QUF9 Q9QWR4
UniProt Splice Variant
Entrez Gene 12268
UniGene
RefSeq NM_009780 XM_006523531 XM_006525280 XM_006536504 XM_006537237 XM_006544477
OMIM
CCDS CCDS28657
HPRD
IMGT
MGI ID MGI:88228
MGI Symbol C4b
EMBL AF049850 AK157954 AK158256 AK158475 BC067394 BC067409 CT573030 D10085 D90167 K00019 K02798 K02799 M11729 M11789 M12968 M12969 M12970 M12972 M14225 M14226 M17440 M23186 X05314 X55493 X55495
GenPept AAA39506 AAA39554 AAA39555 AAA39556 AAA39557 AAA39558 AAA39559 AAA39561 AAA39563 AAA39684 AAA40487 AAC05279 AAC42021 AAC42022 AAH67394 AAH67409 BAA14198 BAA32341 BAE34280 BAE34429 BAE34531 CAA28936 CAA39112 CAA39114
RNA Seq Atlas 102643089 12268

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca